LCMS Sampula Kugadzirira: Kuverengera yedata yedatha neAijiren Caps & Septa
MuLC-ms kuongorora, nhanho dzese dzekuenzanisira dzinogadzirisa, kunyanya sarudzo uye kushandiswa kwemapipi eVial uye Septa. Ichi chinyorwa chakarongeka chinokoshesa nzira dzinogadzirira, kusanganisira filtration, protein lippitation, nzvimbo yakasimba yekubvisa, mvura-yemvura yekubvisa, inotsigira mvura yekubvisa mvura, uye kuderera. Inotsanangurawo mashandisiro okusarudza eijiren's Pre-slitone Netafura yekufananidza yechigadzirwa, vaverengi vanogona kunyatsonzwisisa zvakanakira uye zviitiko zvekushandisa zvechiputi chega chega?
Nhanganyaya
Mune zvemvura chromatography-misa spectrometry (lc-ms), kugadzirira kwakakodzera kwakakosha kuwana mhedzisiro chaiyo, yakavimbika. Maitiro aya anobvisa, anochenesa, uye anokoshesa chinangwa chekuongorora matrices akaomarara kana achibvisa zvipingamupinyi zvinosvibisa data. Semple-mhando sampuli plully inosimudzira kunzwa uye chokwadi, icho chakakosha kune minda senge mishonga yekuongorora, protomics, uye kuyedzwa kwezvakatipoteredza. Diki diki dzakadai seVial kuvharwa kunogona kuita mutsauko mukuru: kusvibiswa kana kusvibiswa kubva kumararamiro emakapu \ / / Septa anokanganisa muenzaniso usati watosvitsa lc-ms.
Key Pfungwa: Shandisa Aijiren's Professional Caps uye Septa Kuti udzivise Sampula Kusvibiswa uye Guarantee Data Kutendeka kweData.
Nyika-ye-art lc-ms chiridzwa mune laboratory, inoratidza kukosha kwekugadzirira kwemuenzaniso kugadzirira.
1. Zvakajairika lcms sample yekugadzirira maitiro
| Maitiro | Chinangwa |
|---|---|
| Filt | Inobvisa zvikamu (0,2 μm mafirita) kuchengetedza makoramu uye nozzles. |
| Protein Wrickitation | Inoshandisa organic sol solventes (acetonitrile, methanol) kusvika kuRearton puroteni kubva ku bio-samples. |
| Solid phase yekubvisa (SPE) | Inoisa pfungwa yekuongorora uye kubvisa kupindira kuburikidza nehuremu cartridges. |
| Liquid-Liquid Exction (LLLE) | Shanduko inoongorora mu organic chikamu; zvakasiyana-siyana asi zvinogona kuyera. |
| Inotsigira mvura yekubvisa | Automated lle pane inert inotsigira; inodzivisa emulsion uye inochengetedza sol sol. |
| Derivatization | Chemakemikari inogadzirisa Ongorora (i.e. Methylation) kuvandudza ionzation. |
2. CAPS uye Septa: Vachengeti vevatengi vevatengi
MuLC-ms anoshanda, iyo vial kuvharwa ndiyo yekupedzisira chipinganidzo pamberi pekuongorora. Yakakwirira-mhando Septa uye CAPS inove nechokwadi chekusimbirira masheya, kudzivirira kubuda kwevachechi uye kuvharira zvakasvibiswa kwezvakatipoteredza.
- PTFE \ / Silicone Septa: CHEMICOCY inert, kuderedza mapepa.
- Yakabikwa CAPS: Septum yakasungirirwa zvachose kune iyo cap, inobvisa zvidimbu zvakasununguka uye ichine zvisimbiso zvisingabvumirani.
Zvakakodzera Capnic technoque Zvakare Zvakakosha: Simbisa Snugly-pamusoro-Kuwedzeredzwa kunogona kubviswa Septa, pasi-kusimbisa kunokonzeresa kubhururuka. Chisimbiso chakachengetedzeka, yunifomu inovandudza kubereka uye kudzivirira kuyambuka-kusvibiswa.
3. Kufananidza caps \ / Septa kugadzirira nzira
| Kugadzirira | Yakakurudzirwa Kuvharwa | Sei? |
|---|---|---|
| Filt | Standard ptfe \ / silicone septum + yakasimba screw cap | Inert chiso inoramba solventes; inodzivirira kutsikisa kutakura. |
| Protein Wrickitation | Pre-Slit PTFE \ / Silicone Sepum + Screw Cap | Inobvumira inodzokororwa autosampler punctures pasina kubviswa cap. |
| Pfunga | Pre-Slit PTFE \ / Silicone Sepum + Screw Cap | Anomhanyisa jekiseni jekiseni; inochengetedza chisimbiso panguva yekuchengetedza. |
| LLLE \ / Yakakudzwa | PTFE-Yakatarisana Septum (PTFE \ / Silicone Sandwich) + yakasungwa cap | Inopesana nemhondi; dhizaini rakabikwa rinodzivirira septum shuwa kana kuzvimba. |
| Derivatization | Yakabikwa PTFE \ / Silicone Sepum + Aluminium cap | Inopa chisimbiso chenguva refu kurwisa kubuda kwemucheka uye unyoro rinogona. |
4. Ahijiren Cap & Sept Chigadzirwa Kuenzanisa
| Chigadzirwa mhando | Zvinhu | ZVINOKOSHA ZVINOKOSHA | Zvishandiso |
|---|---|---|---|
| Pre-slit ptfe \ / silicone screw cap | Ptfe \ / silicone Sepum + aluminium cap | Kudzokororwa puncture; iner; yakaderera inobvisa | Yakakwira-incutput lc-ms, autosampleers |
| Standard ptfe \ / silicone screw cap | Ptfe \ / silicone Sepum + aluminium cap | General-Chinangwa Chisimbiso; yakafara solvent kujekesa | Maitiro eLC-ms vials |
| Yakasungwa septum crimp cap | Al cap + yakasungwa septum | Septum yakasungirirwa zvachose; inosanganisira chisimbiso chemahara | Otomatiki masisitimu, kureba-kwenguva kuchengetedza |
| Snap cap + rabha septum | Rubber Septum + isina simbi simbi clamp | Mutengo wakaderera; njodzi yeKora | Budget-inonzwa, isina-kuongorora kuongorora |
Tafura: Ahijiren kuvharwa & Septa Chigadzirwa Kuenzanisa.
Mhedziso
Inobudirira LC-ms Sampling kugadzirira ndiyo hwaro hwehuwandu hwakavimbika imbeu. Uchishandisa kuvharwa kwakaringana - seAijiren's Pre-Slit PTFE \ / Silicone Septa uye yakasungirirwa Caps-inochengetedza kutendeka kwemumiriri nekudzivirira kusvibiswa uye nekuvhura. Kufananidza kuvharwa kwenzira yako kunoita kuti uwane chaiyo, mubereki mibairo. Zvekuongorora Lab, pharmaceutical R & D, uye yechitatu-bato kuongorora Labs
Key Kutora: mhando vial caps uye septa yakakosha kudzivirira kurasikirwa kwekuenzanisira uye vimbiso yekuongorora yekuongorora. Aijiren's Sealing Solution Salutions inosimudza LC-ms performance uye laboratory kushanda.
