Daga m acidic ruwan magani zuwa lipophilic kwayoyi, zabar samfurin da ba daidai ba zai iya fadada murhun ciki ko kuma ya haifar da kololuwa fatalwa. Wannan jagorar ta rarraba iyakokin wasan soda-lemun tsami vs. Borosilicas gilashin da aka yi da kuma ba da dabarun binciken da aka samu zuwa ayyukan yau da kullun.

Bukatun samfurin & aikace-aikacenku

Tattalin arziki	Samfurin hali	Mall Buga bukatun
Muhalli	Acidic madara (pH 1-3)	Juriya na juriya; sifili mai karfe
Firrari R & D	Apis narkar da a cikin acetonitrile	Kwayar halittar kwayar cuta; low adsorption
Gwajin abinci	Filastik a cikin man kayan lambu	Rashin daidaituwa na lipophilic; kariya ta haske

Kwatancen aikin kayan aiki

Abu	Halayen key	Daidaituwa da daidaituwa	Kudin (€ a kowace vial)	Yi amfani da lokuta
Gilashin lmen-lmim	Akalla tsada	PH 6-8 kawai	~0.5	Koyarwa game da; ruwa mai gajere
Low-borosilicate	Asali na acid resistance (ph ≥4)	Ba hf- ko tushe mai ƙarfi	★★☆☆☆	Yau da kullun hplc ruwa assays
Matsakaici-borosilicate	pH 0.5-10; Autoclavable a 120 ° C	M ph; zafi-m	★★★☆☆	Firama Qc; Samfuran Bio
Babban-borosilicate	Matsananci pH 0-14; da gangara ta tabbata	Duk acid \ / sansanoni; 500 ° C iya iyawa	★★★★☆	Trace \ / HARD--AC AILD

SAURARA: Matsakaici-Borosilicate saduwa da USP \ / ep magabtattun ƙa'idodin gilashi. High-BOROSIVICAT CETE ≈3.3 × 10⁻⁶ \ / k vs. 9 × 10⁻⁶⁻⁶ \ / k don gilashin talakawa.

Zabi SEPTA ta dama

Nau'in septum	Binciki rayuwa	Daidaituwa da daidaituwa	Rikici	Manufa don
Ptfe \ / silicone hade	15-20 sun yi huji	Acid, bots, matsakaici karuwa	DMF na iya delaminate	Hplc autosampleg gudu
PTFE PTFE	Guda amfani	Duk abubuwan da ke cikin kwayoyin halitta	Talauci mai kyau	GC-ms halogened asays
Pre-zura silicone	30+ sokin	Rauni acid \ / Bases (PH 3-10)	Swees a cikin acetone	Hanya mai Hanya

Abubuwan da Vial & Seepta shawarwari na samfurin

Samfurin samfurin	Shawarar da aka ba da shawarar	Zabi Septum	Tashin hankali don gujewa
Tonan masana'antar (pH 1.5)	Babban-borosilicate bayyananne vial	Farin ptfe / silicone hade	Karka yi amfani da soda-lemun tsami (rassan a cikin 24 h)
Miyagun ƙwayoyi a cikin acetonitrile	Matsakaici-borosilate vial	Blue tsarkakakken ptfe	Low-borosilaicate yana kaiwa zuwa ga ener ta
Kayan lambu na kayan lambu	Amber High-Borosilicate	Pre-zura silicone	Share gilashin yana buƙatar kariya ta haske
Koyar da Bugfers (tsaka tsaki)	Soda-lemanni gilashin vial	Tabbataccen Silicone	Kawai don ɗan gajeren lokaci, samfurori masu tsaka tsaki

Nazarin Kasa: Rashin Canja wurin Hanyar Canja wurin

Saita na asali:
- Samfura: API a cikin 0.1% formic acid \ / acetomrile (1: 1)
- Ganga: low-borosilicate Vial + Standard Silicone Silicone Silicone Silicone Silicone
Batutuwa:
- Ba a sani ba koren da ba a sani ba akan allura # 3 (masu hayaƙi)
- API abun ciki ya saukar da 12% bayan 72 h (adsorption gilashin)
Magani:
- Haɓakawa zuwa matsakaici-borosilicate hydrolyTil gilashin vials
- Sauya zuwa lokacin farin ciki PTFO \ / silicone hade da SEPTA (pre-perced 5 ×)
Sakamakon:
- Fatalwar kololuwa cire
- Bangaren Gwajin Gwaji <0.8%

Maɓalli

Harsh acid → Babban-Borosilicate
Yarjejeniyar Phar Farma → matsakaici-Borosilicate
Samfuran tsaka-tsaki na gajere na gajere na gajere
SEPTA Christry> RAYUWAR SAUKI

Nassoshi bayanai:

USP <660> Gilashin Kwallan Gilashin
Rahoton Cma-Tabbatacce

Tare da wannan jagorar, dace da vial da Septum zuwa sunadarai-gujewa asibitocin da suka dace da tabbatar da bincike na zamani a duk faɗin yanayin muhalli.

A baya:

Menene banbanci tsakanin GC-MS da GC-Ms \ / ms?

Komawa jerin

Tags: HPLC VIals GC-MS Samfura Prop Babban gilashin gilashi matsakaici-borosili Ptfe \ / silicone Selta

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