vials-ka-advals-ka, daaweyn dusha sare ah, vials silalan, vials peg ah, vials vials, pfdcs daboolka

Falanqaynta xasaasiyadda sare, khasaaraha xayeysiinta ee dusha sare ee sagxadaha ayaa xadidi kara saxsanaanta ogaanshaha. Kooxaha isku xirta Silanol (SI-OH) oo raad raac birta cayayaanka ah ee dhalada ah ama is dhexgalka elektaroonigga ah ee leh molecules muunadeed, immobilight polar ama lagu dallaco derbiga fin-ka. Vials-ka dabacsan ee aan la daaweyn badanaa waxay dhalisaa daroogada polar ama bayoolajiyada ka hooseeya 80%, iyo sheybaarka muunad qaadista otomaatiga ah ayaa ku dhaca suuxdin muhiim ah oo ku saabsan barbaarka soo noqnoqda. Iibiyaasha ayaa kula talinaya finanka muraayadaha muraayadaha indhaha ee loo yaqaan 'polar' ee loo yaqaan 'polar' ee loo yaqaan 'polar' ee loo yaqaan 'polar' ee loo yaqaan 'polar' ee loo yaqaan 'Polar' Sidaa darteed, soo-dejinta dusha sare ama daaha ayaa muhiim u ah saxsanaanta heerka raad-raaca.

2. Goobaha Firfircoon Glass Firfircoon iyo qaabab xayeysiis ah

a. Kooxaha Silanol iyo ionsiga birta
  i. Kooxaha dusha sare ee SI-Oh waxay xidhaan falanqaynta Polar si aan macquul ahayn
  II. Raadinta farriinta birta ah waxay ku dhacdaa is dhex galka elektaroonigga ah ee moleekulada lagu soo oogay

b. Solven shoog
  i. Soctents dabiici ah (E.G., ACN, Meh, Meh) ayaa xallin karta lakabyada damaca, oo muujineysa goobo cusub oo firfircoon

c. Hawada
  i. Dabaqa haraaga ah ee lagu soo oogay ama molodrophilic-ka ku dhaca derbiga ayaa soo saara paks cheaks ah oo ku xigta

d. Saamaynta nidaamka otomaatiga ah
  i. Cirbado soo noqnoqda ee nidaamyada wax soo saarka ee wax soo saarka ah waxay kordhiyaan dabinka loo yaqaan 'Polar' ama falanqaynta raad raac
  II. Guuldarooyinka la soo sheegay ayaa had iyo jeer ka badan 10% waqti ka dib

3. Mabaadi'da daaweynta dusha sare

3.1 Qalabka Dhaqanka

a. Feejignaan heer-sare ah (~ 800 ° C)
  i. Qabow xoogaa si-oh laakiin waxay ka tagaysaa ion-ka birta

b. Cuntooyinka Acid (E.G., 6 m hcl)
  i. Waxay meesha ka saartaa ionsiga birta laakiin dusha sare ee dhalada

c. Websaydh salka (E.g., 1 M Nax)
  i. Waxay abuurtaa goobo dheeraad ah oo Si-O⁻ ah, mid ka hortag ah

d. Xadidaadaha
  i. Kaliya dhimista qayb ka mid ah goobaha firfircoon ee substrate dhalada

3.2 Silalan

a. FARSAMADA FARSAMADA EE KU SAABSAN SHAQADA
  i. Abaabulan (E.G., methylsilane) Foomka Dambi-guurka Si-O-SI DEDPS oo leh dusha sare ee Silanols
  II. Waxay abuurtaa caqabad hydrophobic ah oo ka hortaga kuleylka, aashitada, iyo saldhigyada
  III. Waxay yareysaa xiisadda dusha sare oo waxay dib u soo celisaa polar andyte ka soo kabashada in ka badan 90%

b. Tusaalooyin iibiyayaal ah
  i. "DV" vials Silalaned oo loogu talagalay falanqaynta guryaha (biyuhu)

3.3 Xirmooyinka Hawlaha Shaqada

a. PerfluoDycylthictylososile (PFDCs)
  i. Is-ururinta Monolayer wuxuu soosaaraa dusha sare
  II. Ku habboon in aan loo baahnayn pahs iyo wasakhooyinka lipid-sorta

b. Polyethylen glycol (peg)
  i. Xirmooyinka silsiladaha biyo-baxa ayaa iska celiya borotiinnada, agaasinka, iyo falanqaynta biyaha-ku-militariga
  II. Waxay bixisaa ilaalin sare ee biomolecules

4. Qaababka xakamaynta xayeysiinta iyo xogta

a. Dhibaatooyinka xaasiga ah
  i. Lakabyada Sidene ayaa dhaxanta heydrophobic-ga, xannibidda xasaasiyadda polar
  II. Xasilloon kadib markii la dheereeyey ee acn ama Meh

b. Waxqabadka Soo kabashada
  i. Vials silalan-ka ayaa sii wata soo kabashada 100% ee 1-da ppb doxtein waqti ka dib
  II. Vials peg-peg-pegs waxay gaaraan 97-99% ka soo kabashada polar β-nactams in ka badan 72 H iyo 70-80% quraaradda aan la daweyn
  III. Vials vials vials waxay ka badan tahay 90% soo kabashada si loo isticmaalo pahs marka loo eego qiimayaasha ugu hooseeya ee galaaska

c. Darajooyinka Advicorchives ee qaraabada
  i. Falanqaynta Polar: Peg> Silazed ≈ pfdcs>
  II. Falanqeyn-xisaab-bixin: PFDCS> Silalan> DEaccivy> Peg

5. Xulashada dalabka iyo waxqabadka ugu wanaagsan

a. Ku habboon daaweynta tijaabada tusaale
  i. Xeryadaha wakaalada (daroogada, borotiinnada, karbohaydraytyada): Isticmaal jaakadaha simbiriiska ah ama peg
  II. Nornica-galka (pahs, sunta lipophophilic sunta): Adeegso jaakadaha pfdcs
  III. Saamballada isku qasan: Silalan-ka ayaa bixiya waxqabadka dheellitiran

b. Tixgeli xal iyo deegaan
  i. Xarig Silver ah ayaa dulqaadaya pH 1-12 iyo abaabul
  II. Xirmooyinka polymer-ka ayaa laga yaabaa inay hoos u dhigto hoos imaatinka qalalaasaha adag ama kuleylka kulul; Tixgeli galka ptfe-ga ama polypropylene vials xaaladaha ba'an

c. Mugga muunad iyo soo noqnoqoshada duritaanka
  i. Loogu talagalay microvolumes (<100 μl) ama qayb ka mid ah muunad soo noqnoqda, isticmaal jaakad waarta
  II. La socoshada Qeexitaanka Daboolida iyada oo loo marayo xagal la xidhiidha

d. Miisaaniyadda iyo Unial
  i. DIIWAANKA: Qiimaha ugu hooseeya, ku habboon barista ama shaashadaha joogtada ah
  II. Vials Silaland: Qiyaasta dhexe, qiimaha ugu hooseeya, hplc \ / lc-Ms codsiyada
  III. PEG \ / PFDCS: Qiimaha lacagta caymiska, ku habboon bioaneys-yada banaanida iyo raadinta tijaabada deegaanka

6. Gunaanad: Laga soo bilaabo markabka tooska ah ee loo maro interface firfircoon

Sida dareenka falanqaynta ee loo yaqaan 'Fandafadaha' PPB \ / PPB-ga PPB, Muusows Muunad ayaa noqda kuwo firfircoon oo is-dhexgal ah halkii ay ka ahaan lahaayeen weelal aan waxtar lahayn. Daaweynta la beegsaday ee la beegsaday khasaaro aan la saadaalin karin oo ku lunsana xadidayaasha la xakameynayo. Xulashada vial iyo daweyn dusha sare ayaa ah qodobo muhiim ah oo ah heerka-hoose. Iyada oo la isbarbar dhigto tikniyoolajiyadda dahaarka ah si loo baadiyo kimistariga, shaybaarada waxay u rogaan vials aaladaha saxda ah, si weyn u wanaajinaya sax ahaanta iyo taranka ee falanqaynta raadinta.

Falalka Muhiimka ah

1. Falanqaynta loo yaqaan 'ultra--xasaasiyadda', isticmaal vials-ka la dhimay ama dahaarka ah

2. Isbarbardhiga Fority: Silalan \ / peg loogu talagalay hydrophilic, pfdcs for hydrophobic

3. La soco daboolka

4. Isku dheellitirka qiimaha iyo tayada xogta