Lati omi ekikan strowly si awọn oogun lipophilic, ti o yan vial apẹẹrẹ apẹẹrẹ le jamba tabi okunfa phant Phant. Itọsọna yii pọ si awọn idiwọn iṣẹ ti omi onisuga-orombo la omi kekere ati nfunni awọn ọgbọn-andpa ati ilana iṣapẹẹrẹ ti o fa awọn ohun elo ti o fa nipasẹ awọn iwalaaye awọn ohun elo ti o fa.

Awọn ibeere rẹ ati awọn ibeere ohun elo

Ile iṣẹ	Ayẹwo aṣoju	Awọn iwulo bọtini bọtini
Agbegbe	Ekikan estewater (PH 1-3)	Igbẹkẹle ti ogbele; leach irin
PARHA R & D	APIS tituka ni acetonitrile	Logan Organic; Ajọ
Idanwo ounje	Rasizers ni epo Ewebe	Oludari lipohoholic; Idabo ina

Ifiweranṣẹ iṣẹ-ṣiṣe

Oun elo	Awọn ami pataki	Ibamu ohun elo	Iye owo (€ fun Vial)	Lo awọn ọran
Gilasi onisuga	O kere ju gbowolori	PH 6-8 nikan	~0.5	Awọn aami idile; omi kukuru kukuru
Kekere-borosilicate	Ipilẹṣẹ Acid ipilẹ (PH ≥4)	Kii ṣe HF- tabi ipilẹ-sooro	★★☆☆☆	Ilana Isun omi Hplc
Alabọbọ-Borosilicate	ph 0,5-10; autoclavable ni 120 ° C	Nink; igbona-sterilivalidable	★★★☆☆	Chaff QC; Awọn ayẹwo Bio
Giga-borosilicate	Awọn ti o gaju PH 0-14; gbona idurosinsin	Gbogbo awọn acids \ / awọn ipilẹ; 500 ° Carable	★★★★☆	Wa kakiri \ / awọn itupalẹ ibinu

AKIYESI: Alabọde-borosilicate homets \ / ep elegun gilasi awọn iyaworan. Giga-borosilicate CTE ≈3.3 × 10⁻⁶ \ / k. 9 × 10 \ / k fun gilasi arinrin.

Yiyan ọtun seto

Tẹ apẹrẹ	Lilu aye	Ibamu ohun elo	Iyọkuro	Apẹrẹ fun
Ptfe \ / Silikone Persite	15-20 Piercings	Awọn acids, awọn ipilẹ, awọn epo	DMF le ṣe imulẹ	Hpl Autosampler gbalaye
Ptfe funfun	Lilo ẹyọkan	Gbogbo awọn nkan ti Organic	Egbin ti ko dara	GC-Ms haleganated assys
A pre-gba silicone	30+ Lilu	Awọn acids alailagbara awọn alailagbara (f ph 3-10)	Whicks ni acetone	Awọn iboju iboju giga

Vial & Septa Awọn iṣeduro nipasẹ apẹẹrẹ

Iru ayẹwo	Ti a ṣe iṣeduro ewe	Yiyan Exptum	Pipfall lati yago fun
Ile-iṣẹ ile-iṣẹ (PH 1.5)	Alailori ti o ga julọ	Funfun ptfe \ / sirikone compusote	Maṣe lo omi onisuga
Awọn impurities oogun ni acetonitrile	Bi alabọde-borosilicate	Vtre buluu funfun	Awọn aladari kekere
Awọn afikun epo Ewebe	Amber ga-borosilicate	A pre-gba silicone	Kosi Gilasi Kalisi nilo Idaabobo Imọlẹ
Awọn ajekii ti nkọ (didoju)	Onisuga-orombo wewe	Boṣeji siliki	Nikan fun igba diẹ, awọn ayẹwo didoju

Iwadi ọran: ọna gbigbe ọna iyipada ni Pharma

Eto atilẹba:
- Apejuwe: API ni 0.1% Acid Acid \ / Acetonitrile (1: 1)
- Eiyan: vialosilicate vial kekere + silicone Seplum
Awọn ọran:
- Awọn ibi giga ti a ko mọ han lori abẹrẹ # 3 (awọn telikonu leackie)
- API akoonu ti a silẹ nipasẹ 12% Lẹhin 72 h
Solusan:
- Igbesoke si alabọde-boringaricasticasticasticac Gilasi thials
- Yipada si Ltfe Ruck \ / Silikone Figusote Septa (Pre-gun 5 ×)
Abajade:
- Phantom peas ti yọ kuro
- Iyatọ idanwo Idanwo <0.8%

Awọn ọna itẹwe bọtini

Awọn ohun acids harss → garosilicate giga
Ifiweranṣẹ Chalma → alabọde-borosilicate
Awọn ayẹwo kekere-kukuru-kukuru → omi onisuga
Cheastry keystest> Live igbesi aye

Awọn itọkasi data:

USP <660> Awọn idanwo eiyan gilasi
Awọn ijabọ lata

Pẹlu itọsọna yii, baamu vial vial rẹ ati Septum si chemistri-yago fun awọn abajade ti o ni idiyele ati rii daju ẹda-ọna kọja ayika ati onínọmbà.

Ti tẹlẹ:

Kini iyatọ laarin GC-MS ati GC-Ms \ / Ms?

Itele:

Pada si atokọ

Awọn afi: Hpl Vials Gc-ms apẹẹrẹ nse Awọn ẹya gilasi giga-borosilicate Alabọde-borosilicate awọn ọmọ wẹwẹ Ptfe \ / Silikọ Septa

Ibeere