I-Vials ye-Adsorction, unyango lwe-vial veres, i-vials ye-SILADE, i-vials edityanisiweyo, i-PFDCs

Kuhlalutyo oluphezulu, ilahleko ye-adsorction kwimiphezulu ye-vial incomes inokunciphisa ukuchaneka. Amaqela e-Inrinsic SILanol ​​(i-SIA-OH) kunye nokungcola kwentsimbi kwiglasi ye-hydrogen ye-hydrogen okanye unxibelelwano lwe-elektrostatic kunye neemolethi zemolekyuli okanye ipoliselo ye-carling okanye ihlawuliswe imichiza kudonga lwe-val. I-vials enganyangekiyo ye-borosilicicate ihlala ivelisa ichiza lePolar Polar okanye i-biomolecule iphinda iphindwe ngaphantsi kwe-80%, kunye nokuhamba kwesampulu yesampulu yesampulu yesampulu yokutya. Abathengisi bancoma i-vials yeglasi ye-slian yohlalutyo kakhulu kwi-adsorve kwiglasi, kwaye izifundo zibonisa iisampulu zenqanaba le-PPB ziphulukene neglasi engapheliyo kwimizuzu. Ke ngoko, ukudluliselwa komphezulu okanye ukungqubana kubalulekile kumgangatho wokuchaneka kwenqanaba.

I-2. Iisayithi ezisebenzayo zeglasi kunye neendlela ze-adsorction

a. Amaqela eSilanol kunye nee-ion zentsimbi
  i. Umphezulu we-SI-oh amaqela ebopha i-polar parlar
  II. Trace i-ion yentsimbi yeFomu ye-elektrostatic kunye neemolekyuli ezihlawulisiweyo

b. I-Solvent Shock
  i. Izinyibilikisi ze-organic (i.G., Acn, Meoh) zinokudana, ukutyhila izalathi ezintsha

c. Ukungcolisa kwendlela
  i. Iimolekyuli ezihlawulelwayo okanye iimolekyuli ze-hydrophilic eludongeni zivelisa iincopho ze-hopost kwiindlela ezilandelayo

d. Iziphumo ezenzekelayo zenkqubo
  i. Inaliti ephindaphindiweyo kwiinkqubo ezingenamgangatho eziphezulu zonyusa ukungqubana kwePolar okanye i-trace
  II. Ilahlekiso elixeliweyo lithintela i-10% ngokuhamba kwexesha

3. Imithetho-nkqubo yoNyango engaphezulu komhlaba: I-DeActivation vs

I-3.1 yokwakhiwa kwemveli

a. Iqondo lokushisa eliphezulu (~ 800 ° C)
  i. Icoca ezinye-oh kodwa zishiya i-ion yentsimbi

b. I-Acid Hish (E.G., 6 m hcl)
  i. Isusa i-ion yentsimbi kodwa i-rohens iglasi yeglasi

c. Ukuhlanjwa kwesiseko (E.G., 1 m naoh)
  i. Velisa iindawo ezongeziweyo ze-SI-O⁻, ukulungelelanisa

d. Imida
  i. Kuphela ukunciphisa indawo ezisebenzayo kwiglasi yeglasi

I-3.2 i-slilalization

a. Unyango lwe-Organesilane phantsi kweVecuum
  i. I-Organosicanes (E.G., I-Methyllilane) i-CHEAGENT SIAGE YO-SILD nge-SILD SILASOLS
  II. Yenza umqobo we-hydrophobic oxhathisa ubushushu, i-asidi, kunye neziseko
  III. Iphantsi koxinzelelo lomphezulu kunye nokubuyiselwa kohlalutyo lwe-polar kwi-90%

b. Imizekelo yeVendoor
  i. "I-DV" i-vials ye-vilany yomhlaba wokuhlalisa

3.3 Ingubo esebenzayo

a. I-PerfluodectTltrilane (PFDCs)
  i. Ukudibana
  II. Ilungele i-pahs engafakwanga kunye ne-lipid inyibilikisi

b. I-Polythylene Glycol (Peg)
  i. I-Hydrophilic Chains proterins, i-peptides, kunye nohlalutyi-anyibilikayo amanzi
  II. Inika ukhuseleko oluphezulu lwee-biomolecules

I-4. Iindlela zoLawulo lwe-Adsorption

a. Iziphumo zokudluliselwa
  i. I-SILAED DIMTERS INDAWO YOKUGQIBELA I-Gydrophobic, iBlarling Polar Bind
  II. Uzinzo emva kokuntywila kwi-acn ​​okanye ngo-meoh

b. Umsebenzi wokubuyisela kwimeko yesiqhelo
  i. I-vials ye-vilawed igcina i-100% yokuBuyiselwa kwe-1 ppb doxipin ngokuhamba kwexesha
  II. I-vials ye-Peg-iphumelele i-97-99 i-9% yokubuyisela i-Polar β-latons ngaphezulu kwe-72 hlekazi i-70-80% kwiglasi engachazwanga
  III. I-VFDCs Vials idlula i-90% yokuBuyiselwa kwePahs xa ithelekiswa namaxabiso asezantsi kwiglasi engenanto

c. I-adsorvery ye-adsorction
  i. Uhlalutyi-polar: I-PEG> Isibindi
  II. Uhlaziyo lwangaphakathi: PFDCs> Isibindi> I-Speent

5. Ukukhetha isicelo kunye neendlela ezilungileyo

a. Tshatisa unyango kwi-chemistry yesampula
  i. I-polar ceands (iziyobisi, iiproteni, ii-carbohydrate): Sebenzisa i-stilady okanye i-Peg Diayings
  II. I-Inporics Organics (PAHS, TOPOphilic toxins): Sebenzisa i-PFDCS Coyints
  III. Iisampulu ezixubileyo: I-SILLaIRT ibonelela ngentsebenzo esebenzayo

b. Cinga ngesijwili kunye nokusingqongileyo
  i. I-SILAIWE I-SILLAI YAMABALI YABASEBENZI BE-1-12 kwaye uninzi lwezinto
  II. Ingubo yePolymer inokucekeceke phantsi kweengozi ze-oxidizers okanye ubushushu obuphezulu; Qwalasela i-Ptfees okanye i-polyproplene vials yeemeko ezigqithisileyo

c. Isampulu yesampulu kunye nenaliti
  i. I-microvolumes (<100 μl) okanye isampulu ephindaphindiweyo, sebenzisa iingubo eziqinisekileyo
  II. Ukubeka iliso kwi-COORD HEARDE COUTER Angle (> ± 10

d. Uhlahlo-lwabiwo mali luyahambelana
  i. I-DeActivation: Ixabiso eliphantsi, lifanelekile ekufundiseni okanye kwizikrini eziqhelekileyo
  II. I-vials ye-SILADDES: Ixabiso le-Mini-Right, i-HPLC ye-HPLC \ / LC-MS
  III. I-Peg / / PFDCS: I-PFDCS: I-PFDCs Ixabiso le-Premium, ilungele ii-biasalyses ezichazayo kwaye zivavanye uvavanyo lwendalo

I-6. Ukuqukumbela: kwinqanawa yokungena kwi-intanethi

Njengoko imvakalelo yohlalutyo ifikelela kwi-PPB \ / i-PPT yamanqanaba, i-vials yesampulu ibandakanya iindawo ezisebenzayo endaweni yezikhongozeli. Unyango olujolisiweyo lophantsi lwe-adsorvements iguqula ilahleko engalindelekanga kwiiparamitha ezingenasiseko. Ukukhetha i-Vial kunye nonyango lwezinto ezingaphezulu zizinto eziphambili kwinqanaba eliphantsi. Ngokuthelekisa itekhnoloji yokuthobela i-chemistry yesampula, iilebhu zijika kwi-vials kwizixhobo ezichanekileyo, ukuphucula ukuchaneka kokuchaneka kunye nokuzala kuhlalutyo lohlalutyo.

Izenzo eziphambili

1. Uhlalutyo oluqhelekileyo, sebenzisa i-vials edlule

2. Umdlalo wePolacy: Isibindi

3. Ukubeka iliso kumdlalo: Gcina iindawo ezicocekileyo zicocekile, track Angles, zibalekela izithuba, zibeke endaweni yokungaphumeleli

4. Ixabiso lexabiso lexabiso le-vs. Umgangatho wedatha: I-Premium Coasthings inciphisa i-Reruns kunye ne-Port Times