Lapho uxoxa ngokukhethwa kwezinto zokwenziwa aI-Chromatography Vial, umuntu kufanele acabangele ukuthi ihlangabezana nezindinganiso zokuphepha kwezidakamizwa kanye nobumsulwa ababalulekile emsebenzini welebhu. Amabhodlela we-Chromatography ngokuvamile enziwe ngengilazi noma ngepulasitiki, kepha impahla ngayinye inezinzuzo nokulinganiselwa kwayo, ngakho-ke kufanele kubhekwe izici eziningana lapho wenza ukukhetha kwakho.

Okokuqala, ake sibheke amabhodlela wezithombe ze-chromatography ze-glass chromatography. Ingilazi inikeza amandla amahle kakhulu okuqina kanye nokuqina, okwenza kube ngaphansi kokuhlaselwa kwamakhemikhali noma ukuchithwa, okusiza ukugcina ubumsulwa kanye nekhwalithi yomkhiqizo wezidakamizwa. Amabhodlela we-ChromaTography ama-chromatography nawo anokuvela okuhle kakhulu kanye nezakhiwo ze-optical, okukuvumela ukuthi ubheke ngokucacile isimo noshintsho kusampula yakho. Ngalesi sizathu, amabhodlela wezithombe ze-chromatography esesisenye yeziqukathi ezikhethwayo ezindaweni eziningi zelebhu. Kodwa-ke, amabhodlela we-chromatography ama-chromatography angenamikhawulo futhi angaphulwa kalula uma ethathwe ukushaqeka okuqinile noma ukuguquka kwezinga lokushisa, ngakho-ke ukunakekelwa kufanele kuthathwe lapho usebenzisa futhi uzigcine.

Ingxenye emine ye-vial

Izingilazi zeglasi

Izingilazi zeglasiyizinto ezisetshenziswa kakhulu ku-chromatography ngoba zivukile futhi zingamelana namazinga okushisa ahlukahlukene. Ingilazi ye-borosilicate ithandwa ikakhulukazi ngenxa yokumelana kwayo kokusebenzisana kwamakhemikhali okungathinta ubuqotho besampula. Lezi zinhlaka zivame ukuhlangabezana namazinga abekwe ngama-ejensi okulawula njenge-United States pharmacopeia (USP) kanye ne-european pharmacopeia (PHP) e-EUR.

Ama-vials epulasitiki

Izinto ze-polymeric ezifana nePolypropylene (PP) ne-polyethylene terephthalate (pet) nazo zisetshenziselwa izinhlelo zokusebenza lapho ingilazi ingafanelekile khona. Noma kunjalo, niniama-vials epulasitikiziyasetshenziswa, ukucatshangelwa ngokucophelela kufanele kunikezwe ukuze kunikezwe i-solvent kanye nokuhambisana kwesampula ukuvikela ukuguqulwa kwezinto ezingcolile. Abakhiqizi kufanele baqinisekise ukuthi lezi zinhlaka zepulasitiki zihlangabezana namazinga alawulayo ahambelana nezicelo zemithi, kufaka nemihlahlandlela yokukhishwa kwezimali ezikhishwe kanye nokukhazimula njengoba kuchaziwe yi-USP ne-PH.

Abicah \ ptfe Septum

I-Septums ukuthi ama-chromatography vials ajwayele ukwenziwa nge-silicone noma i-polytetrafluoroethylene (PTFE). Lezi zinto zokwakha kumele futhi zihambisane namazinga okuphepha kanye namazinga okuhlanza ukuvimbela ukungcoliswa kwesampula. I-Silicone Septums icatshangelwa ukuqina kwazo nokuqina, ngenkathiPtfe septumsnikeza ukumelana okuphakeme kwamakhemikhali. Zombili lezi zinhlobo kufanele zihlangabezane nezidingo zokulawula zokukhishwa, ama-leaaker, kanye ne-biocomitity.

Crimp caps nezikulufa cap

Ama-CAPS asetshenziselwa ukubeka ama-chromatography vials ngokujwayelekile enziwe nge-aluminium noma ipulasitiki.I-Aluminium crimp capzivame ukusetshenziselwa ukuhlinzeka uphawu oluqinile futhi zivikele ukuhwamuka nokungcola. Ipulasitiki screw cap, ngakolunye uhlangothi, inikeze kalula ukusetshenziswa futhi ilungele izinhlelo zokusebenza lapho ama-vials kufanele avulwe futhi avalwe njalo. Ukuqinisekisa ubuqotho besampula, ama-cap, kungakhathalekile ukuthi bahlangabezana nezindinganiso zobumsulwa kanye nokuhambisana nezinto ezibonakalayo.

Funda ukuthi ungakhetha kanjani phakathi kwe-crimp vial, i-snap vial, kanye nezinsizakalo ze-screw cap vial kule ndatshana enokuqonda:I-Crimp Vial vs. Snap Vial Vs. Screw Cap Vial, Indlela Yokukhetha?

Izici ezi-5 kufanele zibhekwe

Ukungenelela kwamakhemikhali nokuvuselela kabusha

Ingilazi i-indert ngamakhemikhali, kepha amanye amapulasitiki angaphendula ngamakhemikhali athile. Ngakho-ke, kubalulekile ukukhetha izinto ezifanele ngokuya ngezidingo zokuhlolwa kanye ne-ejenti noma ukusetshenziselwa amakhemikhali.

Ukushisa Okushisa Nokucindezela

Uma ukuhlolwa kwakho kudinga izinga lokushisa eliphakeme noma izimo eziphakeme zengcindezelo, impahla ye-chromatomagraphy ibhodlela kufanele ibe nokuvimbela okuhle nokuphikisana nokucindezela ukuvikela ukonakala noma ukulimala ebhodleleni.

Izakhiwo Ezisobala Nezinto Zokukhanya

Izakhiwo ezibonakalayo kanye nezakhiwo ezibonakalayo zibalulekile ezintweni ezihlolo ezidinga ukubonwa okucacile kwesimo sesampula kanye nezinguquko zombala.

Umthelela kanye nokuvuselelwa okuvuzayo

Amabhodlela we-Chromatography kumele abe nokumelana kahle nomthelela omuhle kakhulu wokugwema ukuguquguquka okushintshisi kanye nokufafaza ngesikhathi sokuhamba nokusebenza. Ngasikhathi sinye, i-Bottle cap design kanye nokwakheka kwe-seal kumele kuqinisekiswe ukusebenza kobufakazi obuvuzayo.

Ukuhlanza okulula nokuphikiswa kokugqwala

Izinto ze-Chromatography Bottle kufanele kube lula ukuzihlanza futhi zibe nokumelana kahle nokugqwala kokuqinisekisa indawo ehlanzekile ngaphakathi kwebhodlela futhi igweme ukungcoliswa yizinsalela zamakhemikhali.

Lapho ucubungulaIzinto zokwakha ze-chromatographyUkuhlangabezana namazinga okuphepha emithi kanye namazinga okumsulwa, izici ezinjengokuvuselelwa kwamakhemikhali kanye nokuvuselelwa kwezinto ezibonakalayo, izinga lokushisa kanye nokuphikiswa kwengcindezi, ukucacisa kanye nokuphikiswa okuvuzayo, ukuncipha nokuphindwahla, kanye nokuphikiswa kokugqwala kufanele nakho kufanele kubhekwe. Ubulili nezinye izinto. Ngokucabanga ngokugcwele lezi zinto, ukhetha izinto ezifanele ze-Chromatography Bottle Material, futhi zilandela imiyalo eqinile nezinqubo zokusebenza ukuze zisetshenziswe futhi zinakekelwa, ikhwalithi kanye nobumsulwa bomkhiqizo wezidakamizwa kungavikeleka ngempumelelo, ukuqinisekiswa kokunemba kwemiphumela yokuhlola.

Thola izimpendulo eziphelele zemibuzo engama-50 mayelana ne-HPLC VIALS kule ndaba efundwayo:Imibuzo evame ukubuzwa kaningi ku-HPLC VIALS

Okwedlule:

Ukusebenza uphawu kwe-PTFE \ silicone septa ngaphansi kwengcindezi ephezulu ekuhlaziyweni kwe-chromatomagraph

Olandelayo:

Ukukhetha isihlungi sesokudla sesirinji sokuhlaziywa kokudla nokuhlaziywa kwesiphuzo