Mbale zotsika kwambiri, chithandizo chotsika kwambiri, mitsuko ya Silanchired, Peg Courts, ma PFDC

Mu chidwi kwambiri, chidwi chachikulu, zotayika za Adsorpp pazabwino zimatha kuchepetsa kulondola. Magulu a Silanol Silnol (si-oh) ndikumatula zitsulo zamiyala mu galasi kapena magetsi ojambula ndi mamolekyulu osokoneza bongo kapena owongolera polar khoma. Mbale zosasinthika nthawi zambiri zimakhala ndi polar mankhwala kapena biomolecule amabwezeretsanso pansi 80%, ndipo mapangidwe ogwirira ntchito okhathamiritsa amavutika kuwonongeka kwakukulu. Ogulitsa amalimbikitsa mipanda yagalasi ya silanled a polar okonda kwambiri galasi, ndipo maphunzirowa amawonetsa ngakhale zitsanzo za PPB-ppb zomwe zimataya zigalasi zosasinthika pakatha mphindi zochepa. Chifukwa chake, zokumana nazo kapena zokutira ndizofunikira kwambiri kuti mukwaniritse kulondola.

2. Masamba ogwiritsira ntchito magalasi ndi ma adsorption

a. Magulu a Silnol ndi zitsulo
  i. Pamwamba si-oh oh mangani polarn onlict osasinthika
  ii. Tsatirani zitsulo zachitsulo zimapanga zibwenzi zamagetsi ndi mamolekyulu olipiritsa

b. Solvent Shock
  i. Ordontic solt (E.g.

c. Kunyamula kuipitsidwa
  i. Otsalira okhazikika kapena a hydrophilic pa khoma pakhoma kumapangitsa Ghost Peak

d. Zotsatira Zochita Zokha
  i. Kubwerezedwa mobwerezabwereza m'magulu okwera kwambiri kumawonjezera kupopera kwa polar kapena trace
  ii. Kutayika kwa siginecha nthawi zambiri kumapitilira 10% pakapita nthawi

3. Mfundo zothandizira: Kuchepetsa vs. zokutidwa

3.1 Chikhalidwe Chachikhalidwe

a. Kutentha kwambiri (~ 800 ° C)
  i. Imawononga si-oh koma masamba azitsulo

b. Acid kusamba (E.g., 6 m HCL)
  i. Chotsani ma ayoni azitsulo koma magetsi agalasi

c. Sambitsani (E.g., 1 m Naoh)
  i. Amapanga malo owonjezera a SI-O⁻, azomwe amachita

d. Kuchepetsa malire
  i. Kuchepetsa pang'ono kokha kwa malo ogwirizira pagalasi

3.2 Silanization

a. Chithandizo cha Elosilane Pansi pa Vuvu
  i. Orlossilanes (E.g., Methyllesilane) amapanga zomangira za countrants za Cound
  ii. Amapanga chotchinga cha hydrophobic chomwe chimayamba kutentha, ma acid, ndi zitsulo
  iii. Ochepetsa nkhawa ndikubwezeretsa chinsinsi cha polarte kuposa 90%

b. Zitsanzo za Vendor
  i. "DV" SILilated Mbale za Polar-Compough (Madzi)

3.3 Zopindulitsa

a. Offeracylllllororoolilane (ma pfdcs)
  i. Wodzimana yekha monolayer amatulutsa superhyrophobic pamwamba
  ii. Zoyenera kwa PIPARER THS ndi Lipid-Sesublent

b. Polyethylene Glycol (Peg)
  i. Hydrophilic Maunins amabweza mapuloteni, ma peptides, ndi osungunuka osungunuka madzi
  ii. Amapereka chitetezo chachikulu kwa biomoleclules

4. Makina owongolera ndi deta

a. Zotsatira za Passvation
  i. A Silane zigawo za silane amapereka galasi la hydrophobic, kutsekereza polar
  ii. Khola mutamizidwa kumizidwa mu ACN kapena Meoh

b. Kubwezeretsa magwiridwe antchito
  i. Mbale za Silanchired
  ii. Mbale zokhala ndi peg-zopaka za Peg zimakwaniritsa 97-99% kubwezeretsa polar β-lactams kuposa 72 h mosinthana 70-80% pagalasi losasinthika
  iii. Mbale za PFDCS PRUPS PRORS 90% Kubwezeretsa Pahs Poyerekeza ndi Mikhalidwe Yotsika Kwambiri pagalasi

c. Mbale Adsororption
  i. Polarnictions: Peg> Silanized ≈ ma pfdcs> otsekera
  ii. Kusanthula kwa ma PFUPRY> SFDCS> SILENTE> SEGINATION> Peg

5. Kusankha kugwiritsa ntchito ndi machitidwe abwino

a. Mankhwala othandizira kutsanzira
  i. Polar mankhwala (mankhwala, mapuloteni, chakudya):
  ii. Organics Organics (Pahs, Lipophilic Toxins): Gwiritsani ntchito zokumba za PFDC
  iii. Zitsanzo zosakanikirana: Silanirization imapereka magwiridwe antchito abwino

b. Ganizirani zosungunulira ndi chilengedwe
  i. Zovala za Silne zimalekerera PH 1-12 ndi organictics ambiri
  ii. Mawonekedwe a polimart amatha kuwononga pansi pa oxidizer kapena kutentha kwambiri; Ganizirani zingwe za PTF kapena polypropropylene

c. Kuchuluka kwa mitundu ndi jekeseni pafupipafupi
  i. Kwa ma microvolumes (<100 μl) kapena zitsanzo zobwereza, gwiritsani ntchito zofunda
  ii. Kuwunikira Kutsegukira Kuchita Chikondwerero cha Angle (>> ± 10 ° Shift of kulephera) ndi Kuthamanga Kwathunthu (Silone Peaks (Silone Peaks (Siloxe Peaks (Silone Peaks (Silonane Peak (Silone Faks (Siox) yopanda tanthauzo (Silox) yopanda tanthauzo (Silox) yopanda tanthauzo (Silox) yopanda tanthauzo (Silox) ndi nsonga yazosanja (Siloxey) ndi nsonga yazopanda (Siloxe Peaks (Silox Peaks (Silote Peak (Silone Faks)

d. Bajeti yothandizira
  i. Kuchepetsa: mtengo wotsika kwambiri, woyenera kuphunzitsa kapena zojambula zambiri
  ii. Mbale za Silaneidwire: Mipira yotsika mtengo, yotakata hplc \ / ma ls
  iii. Peg \ / zokumba za ma PFDC: mtengo wa premium, wabwino kwambiri pakuyesa kovuta kwambiri ndikuyesa kuyesedwa kwachilengedwe

6. Kumaliza: Kuchokera ku sitima yapafupi kwambiri ku mawonekedwe

Monga kuwunika kwa kafukufuku PPB \ / malo a PPP, MABODZA AMAKHALA AMAKHALA NDI ZINSINSI ZOSAVUTA. Mankhwala otsika-adsorption otsika amasintha zotayika zosayembekezereka kukhala gawo lolamulira. Kusankhidwa kwapadera ndikuthandizira pamankhwala ndi njira zazikuluzikulu mu kuchuluka kwambiri. Pofananira ndi ukadaulo wokangana kuti azichedwe kamtamboli, ma labotale amasinthana ndi zida zolondola, kukonza bwino komanso kubereka pakuwunika.

Zochita Zofunikira

1. Pakusanthula kwamankhwala, gwiritsani ntchito zidutswa kapena zopota

2. Gwirizanani polanda: Silanuzere \ / peg ya hydrophilic, ma pfdcs a hydrophobic

3. Kuwunika zokutira: khalani oyera

4. Kusamala mtengo vs. data: zokutira premium zimachepetsa reruns ndi zolakwika zabodza