Ho tsoa metsing a acidic acidic acidic ho isa ho lithophilic, ho khetha sampole e fosahetseng ho ka etsa qeto ea ho khutlisa kapa litlhōrō tsa phapanyetsano. Tataiso ena e felisa meeli ea tšebetso ea Solo-lime - e fana ka maano a Via-le-- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Litlhoko tsa hau tsa mohlala

Indasteri	Mohlala o tloaelehileng	Litlhoko tsa senotlolo tsa senotlolo
Tikoloho	Metsi a litšila acidic (ph 1-3)	Khanyetso ea Corrosanion; Leather Leach
Pharma R & D	Apis e qhibiliha ho acetotorile	Ho hanyetsa kharebetso ea khale; Adsorption e tlase
Teko ea Lijo	Malebela ka oli ea meroho	Ho nepahala ha molomo. Ts'ireletso e bobebe

Ts'ebetso ea tšebeliso ea lintho tse bonahalang

Lintho tse bonahalang	Litsela tsa Bohlokoa	Kakaretso ea lik'hemik'hale	Litsenyehelo (€ € ka Vial)	Sebelisa linyeoe
Khalase ea lime ea soda	E theko e boima haholo	PH 6-8 feela	~0.5	Ho ruta masaki; Metsi a nakoana a nakoana
Bofesilicate e tlase	Hand Acid Acid (Ph ≥4)	Eseng hf- kapa e matla	★★☆☆☆	Assages ea "hiplc ea metsi
BORIUM-BORSISISATE	PH 0.5-10; Autoclavable ka 120 ° C	PH; futhumatsa	★★★☆☆	Pharma QC; sampole ea bio
Bofesilaicate	Ph 0-14; e tsitsitseng	Li-acids tsohle \ metheo; 500 ° C e khona	★★★★☆	Trace \ Harssh-acid

Tlhokomeliso: Medium-Borosilicate o kopana le USP \ EP Pharmactication Glass Bohlaba-borosilicate cte ≈3.3 × 10⁻⁶ \ k vs.3 × 10⁻⁶ \ k bakeng sa khalase e tloaelehileng.

Ho khetha Septa e nepahetseng

Mofuta oa Septum	Ho phunya bophelo	Kakaretso ea lik'hemik'hale	Transback	E loketseng
PTF \ Sillicone Copeste	15-20 piercings	Li-acids, li-esses, so soly	DMF e ka lieha	Hplc automanoler e matha
PTFE PTFE	Ts'ebeliso e le 'Ngoe	Li-solvent tsohle tsa khale	Tiiso e mpe	Gc-ms bahlosen bas
SHIFICE SHAFICONE	30+ piercings	Acid acid acid \ bases (ph 3-10)	Ho ruruha ka acetone	Lits'oants'o tse phahameng

Litlhahiso tsa Vial le Septa ka sampole

Mofuta oa sampole	E khothalelitsoe ho ba le vaelel	Khetho ea Septum	Ho sithabela ho qoba
Metsi a litšila a indasteri (ph 1. 1.5)	Bohlaba bo phahameng bo hlakileng	White ptfe \ Sillicone Copeste	Le ka mohla u se sebelise soda-lime (li qhibiliha ka la 24 h)
Litšitiso tsa lithethefatsi ho acetonitrol	Mochini o mahareng o mahareng	Blue Purewn PTFE	Bofesilicate e tlase e lebisa ho taing ea Peak
Mesebetsi ea oli ea meroho	Amber e phahameng-borolicate	SHIFICE SHAFICONE	Glass e hlakileng e hloka ts'ireletso e bobebe
Ho ruta ba buffers (ho se nke lehlakore)	Soda-lime khalase e boima	SITATED SITALY SIGICONE	Feela bakeng sa mehlala e khuts'oane feela, mehlala e sa jeleng paate

Thutong ea linyeoe: Mokhoa o fetolang ho hloleha ho pharma

Sethala sa mantlha:
- Sampole: API in 0.1% ea foromo ea acid \ acetonitrorile (1: 1)
- Sejana: Borosilicate e tlase haholo + e tlase + e tloaelehileng ea silicone septum
Litaba:
- Litlhoro tse sa tsejoeng li hlahile ka ente # 3 (silicone lebhabhab)
- Litaba tsa Api li ile tsa theoha ka 12% kamora 72 h (Adsorption ea khalase)
Tharollo:
- Ntlafatsa ho li-tydrolytic li monate li-hydrolytic
- Fetolela ho tetero e tenehileng ptfe \ Sillicone Copesteite Septa (Pre-timed 5 ×)
Phello:
- Phantom Peaks e felisitsoe
- Sekhahla sa tlhahlobo ea botsitso <0,8%

Key Picaways

E mpe acid → borena bo phahameng haholo
Phatlalatso ea Phapanyetsano → Borosilicate
Sampole e khuts'oane ea nako e khuts'oane → soda-lime
Septa Chemistry> Ho phunya bophelo

Litšupiso tsa data:

USP <660> Liteko tsa sejana sa khalase
CMA-Certied ChatheSible Lab

Ka tataiso ena, bapisa le phapang ea hau le Septum ho Khetho-ea Chemistring le ho netefatsa sephetho sa tšebetso le phalleng.

E fetileng:

Phapang ke efe lipakeng tsa GC-MS le GC-MS \ MS?

E 'ngoe:

Khutlela lenaneng

Litags: Li-pilc tsa hipc GC-MS sampole ea Prito? Li-glas tse phahameng tsa khalase tse phahameng tsa khalase Li-glass tse nang le bo-'masium tse mebala-bala PTF \ Sillicone Septa

Botsa