Mohlala o pheteloang

Sesebelisoa se nepahetseng sa mohlala, setlolo se hloekileng sa sepakapaka, se tlosa lintho tse ngata, 'me haeba ho hlokahala, li hlahisa litlhōrō tse phahameng le linaha tse tsitsitseng. Ho sitoa mona ho hlaha litholoana tsa tlhoro ea tlhoro, li-sesira tse hohelang, kapa li-bloling blackage.

1. Pontšo le matrix

Bothata

• Meeli ea motheo le ho phahama ha litlhōrō tse nyane.

• Lithako tse sa lebelloang li hlaha li tsoa ho litšila tse lebisitsoeng.

• Ho hlahisa liphoso tse mpe lipakeng tsa ente.
  

  

Baka

• Lits'ebeletso tsa likhukhuni ea Glassware: makhasi a hlala a acid ea acid polasetiki e ka pateloa maselamosetiki.

• Basebetsi ba Hloekisang: Mefuta e meng ea masoha ho li-shols tse sa feleng li lula li ferekane.

• Karolo ea tikoloho: Lehalaleli la lab le lahl and adsorb ho sampole e bulehileng.
  

  

Tharollo

1. Sekhahla se thatafatsang: Asiti ea acid e → sephiri se ne se le se lebelletsoeng ka polasetiki.

2. Pele ho: Centrifuge ho 3000rpm bakeng sa 10min kapa ho sebelisa prefilter ea 5μm pele ho nako ea ho qetela 0,22μm.

3. Tikoloho e laoloang: E etsa pele ho lading ea phallo ea laminar ho fokotsa tšilafalo ea sefofane.
   
   

2. Filter Clogging from Filters e sa lumellaneng

Bothata

• Autosampler Khatello ea Alarms le Liphetoho tsa Nako ea Nako.

• Sekhahla se phatlohileng sa phallo e fokotsehileng, libaka tse sa lumellaneng.

• Mokokotlo o phahameng oa mokokotlo le kolu ea likokoana-hloko.
  

  

Baka

• Membrane Mismsatch: Nylon Hlakola ka li-solvents tsa khale; Pvdf e fana ka mocheso o phahameng.

• Sekhahla se sa nepahalang sa Pore: Lifilimi tsa 0,22LoM li tšoasa ka likarolo tse ntle empa li fokotsa phallo; Lifilimi tsa 0.45μme li kanna tsa koaloa ka li-microcrystals.

Tharollo

1. Membrane-solt Mattrix: Sebelisa hydrophilic pes \ mce bakeng sa ho akheha (ph4-8), hydrophobic pmfephobic pvdf bakeng sa mekhahlelo ea manyolo; Qoba Clilouse Acetase acetis e matla.

2. Khetha boholo bo nepahetseng ba pore: Sebelisa 0.45μm bakeng sa li-hiplc, 0.22μm bakeng sa uhplc kapa mosebetsi oa parce; li-sample tsa prefilter tse phahameng ka ho fetisisa

3. Shebini ΔP: Pina e hlaha; Pheta sefahleho ha backpression e eketseha> 15%.
   
   

   

3. Solvent-membrane

Bothata

• Sampole ea tlhopa e shebahala e le maru kapa e jarolla likokoana-hloko.

• Nomoro e ncha ea motheo kapa lerata la moea oa moea.

• Fokotsa ho fola.
  

  

Baka

• Solvent Ruling: THF e thunya PTF, e fetolang seriti le phallo.

• Membrable ea Lemblone: ​​nylon ho theha foromo ea foromo e abeloang li-ogolisb ka 214nm.

Tharollo

1. Teko ea tumello: Mofuta oa Soak o ikemiselitse ho ba oveven a ho fihlela 24h ka 25 ° C; Lekola ho ruruha kapa ho fetoha hoa boima ba 'mele.

2. Pilot LC-MS Teko: Bapisa kakaretso ea li-chromamagraph tsa tlhojana tse sirelelitsoeng v.

3. Sebelisa li-filthara tse tlaase Low-Leach: Ea ultranosic-weld e nang le ptfe e hlokang kapa e se nang merabe.
   
   

Sisteme ea boleng: Ho beha leihlo-hloko

Ts'ireletso

Timatsa lintla bakeng sa ho hloekisa, ho ile ha hloekisa khetho ea tokoloho ho thibela liphoso.

Ho beha leihlo

Rekota Sekhahla sa Phallo, Backpressure le linaha tsa mehlala tse se nang letho bakeng sa ho lemoha.

Khalemelo

Boloka tlhahlobo ea sefate ea molato bakeng sa tlhahlobo ea metso e potlakileng ea ho fumana metso le ts'ebetso ea khalemelo.

"Ho hlakile hore ho hlakile hore ho tla qala ka ho hlompha karolo e nyane haholo."