Key Differences Between HPLC and GC Vials – Comprehensive Buying Guide

I. Key Differences Between HPLC and GC Vials

1. Application Scenarios

HPLC Vials: Mainly used in High-Performance Liquid Chromatography (HPLC) and LC-MS analysis, suitable for non-volatile, thermally unstable, or light-sensitive samples.

GC Vials: Used in Gas Chromatography (GC) and GC-MS, requiring high heat resistance (usually >300°C) and compatibility with volatile solvents.

2. Material and Design Features

Vial Neck Types:
HPLC: Commonly use screw tops or snap tops, ideal for repeated access and auto-samplers.
GC: Usually crimp top vials with aluminum caps and PTFE/silicone septa for high-temperature sealing.