Top 3 Reasons Why Glass Chromatography Vials are Better Than Plastic Vials

Top 3 Reasons Why Glass Chromatography Vials are Better Than Plastic Vials

Jul. 18th, 2023
Selecting appropriate vials for sample storage and preservation in chromatography is of utmost importance. Deciding between glass or plastic vials can have a major effect on analytical results; here we discuss three of their main advantages over plastic counterparts - superior sample integrity, greater chemical compatibility, and longer term dependability are just three such features that stand out.

Reason 1: Unrivalled Sample Integrity

Glass chromatography vials are widely acclaimed for their inert properties, making them an excellent way to protect sample integrity. Unlike plastic vials, which may interact with samples, glass vials provide minimal interference during analysis - especially critical when dealing with sensitive applications where even trace contamination could skew results - giving researchers confidence in the accuracy and reliability of their data by employing glass vials.

Plastic vials pose potential issues that can compromise sample integrity. Interaction between plastic materials and samples increases the risk of contamination; such interactions introduce impurities into analysis which decrease its quality. Opting for glass chromatography vials to ensure accurate results is vitally important.

Reason 2: Improved Chemical Compatibility

Glass chromatography vials provide significant chemical resistance advantages over plastic vials, providing researchers with greater assurance when working with various solvents and samples that the vials will not compromise their analytical results. They are immune to acids, bases, and organic solvents without reacting with either them or leaching any substances into them, ensuring both samples and analysis remain intact without interference from vials interacting with each other or leaching out materials into it. Therefore researchers can safely work with various solvents or samples with confidence knowing their experiments won't compromise their experimental outcomes due to Glass' chemically resistant capabilities.

Plastic vials have certain limitations with regards to chemical compatibility. Certain plastic materials may react negatively with certain solvents or samples, potentially altering sample composition and impacting analysis accuracy. To reduce risks related to chemical interactions while upholding sample integrity, researchers should opt for glass chromatography vials as they will prevent unnecessary interactions and interferences with sample integrity.

Reason 3: Long-Term Reliability

Durability should always be taken into consideration when choosing vials for long-term storage, with glass chromatography vials standing out as particularly reliable options in this respect. Their construction allows them to withstand various environmental conditions without suffering structural integrity loss and UV exposure, without leakage or breakage compromising stored samples.

Plastic vials raise concerns regarding long-term reliability. Over time, their material could degrade leading to deformation or structural weakness and increasing leakage risks compromising sample integrity. Researchers who depend on long-term storage should opt for glass chromatography vials as a safe storage option to protect their samples and ensure their integrity is preserved.

Glass Chromatography Vials Offer Multiple Benefits

Glass chromatography vials boast many additional benefits that contribute to their superiority, including their optical clarity which allows for easy visual inspection of samples during analysis and recycling capabilities which help promote sustainability while reducing environmental impact. Furthermore, they demonstrate versatility and compatibility with various chromatography techniques catering to researchers across various fields.


Glass chromatography vials outshone plastic vials in multiple critical aspects for successful chromatographic analysis. Their superior sample integrity, enhanced chemical compatibility, and long-term reliability make them the go-to option among researchers. By choosing glass vials instead, researchers can optimize their workflows while still getting accurate and reliable results while protecting the integrity of their samples.