8-425 Caps & Silicone Septa
Product
    • Complete 8-425 Caps and Silicone Septa Set
    • PTFE and Silicone Septa Material Layers
    • Pre-slit Silicone Septa for HPLC Autosamplers
    • Vial Septum Compatibility with Leading Autosamplers
    • 8-425 Cap 5.5mm Small Opening Specification
    • Leak-proof Performance of Customizable Lab Seals
    • Multiple Colors for Customizable Lab Seals Caps
    • Professional Bulk Packaging of Vial Septum
    Complete 8-425 Caps and Silicone Septa Set

    8-425 Small Opening Caps and Silicone Septa with Customizable Lab Seals for Vial Septum

    Professional 8-425 chromatography closures featuring high-purity silicone septa and precision-engineered caps. Our vial septum solutions are optimized for ultra-low bleed and superior resealability in HPLC/GC-MS analysis. Explore customizable lab seals designed to protect your samples and prevent autosampler needle damage during high-throughput sequences.
    Thread Type 8-425 Standard Screw Thread
    Material High Purity PP (Cap) / PTFE & Silicone Septa
    Design 5.5mm Small Opening / Precision Vial Septum
    Compatibility Agilent, Waters, Shimadzu, Varian Autosamplers
    Custom Service Customizable Lab Seals (Slit, Color, Material)
    Description
    Feature
    Specification
    Application
    Product
    FAQ
    Related Articles
    Packing and Delivery

    Precision Sealing for Volatile Lab Samples

    Our 8-425 small opening design minimizes solvent evaporation during long-sequence HPLC/GC runs, ensuring analytical consistency.
     The precisely calibrated 1.5mm thickness of our vial septum ensures a zero-clearance mechanical fit within the 8-425 thread. This design eliminates the risk of septum dislodgement or vacuum formation during high-speed aspiration, maintaining the integrity of volatile samples even during unattended 48-hour sequence runs.

    Advanced Silicone Septa Technology

    High-purity materials for reliable chromatography results.
    Platinum-cured silicone septa for ultra-low bleed.
    Chemically inert PTFE layer resists aggressive lab solvents.
    Multiple vial septum slit options (Y-slit, Cross).
    Precision 1.5mm thickness ensures zero-leakage fit.
    Customizable lab seals available for unique specs.

    Ensuring Lab Compatibility

    Procurement Decision Support
    Material Purity & Sample Integrity
    Selection Guide by Lab Application
     
    Thread Standard 8-425 GPI Standard Agilent, Waters, Shimadzu, Varian
    Vial Type Small Opening Vials All 2mL 8-425 Screw Neck Vials
    Vial Septum Size 8mm Diameter Precision fit for 8mm cap aperture
    Needle Type Standard & Thin Gauge Optimized for 22G to 32G needles
    Autosampler High-throughput systems Reliable for 24/7 automated sequences

     

    Component Material Grade Lab Benefits
    Silicone Septa Ultra-pure, Platinum-cured Low Bleed: Prevents ghost peaks in GC/MS
    Liner Material High-inertness PTFE Chemical Shield: Resists DCM, ACN, Hexane
    Cap Material Laboratory-grade PP No Leaching: Zero plasticizer interference
    Hardness 45-55 Shore A Resealability: Safe for multiple injections
    Cleanliness Dust-free processed Zero Contamination: Protects trace samples

     

    Application Recommended Vial S Primary Advantage
    Routine HPLC Analysis Non-slit White PTFE/Red Silicone Maximum sealing for standard runs
    Sensitive GC/MS Trace High-purity Silicone Septa Ultra-clean baseline, no siloxane interference
    High-Throughput / Thin Needle Pre-slit (Y-slit/Cross) Septa Reduces needle drag and prevents bending
    Volatile Sample Storage Bonded PTFE/Silicone + Closed Cap Customizable Lab Seals for zero evaporation
    Aggressive Acid/Base Double-sided PTFE (PTFE/Silicone/PTFE) Dual-layer protection against corrosion

    Professional Application Scenarios

    Beyond standard specifications, we understand the critical pain points in daily laboratory operations—from baseline noise in MS to needle fatigue in high-throughput systems. Our customizable lab seals and silicone septa are engineered not just to fit a vial, but to provide a robust solution for your most demanding analytical environments.
    Eliminating Baseline Ghost Peaks
    Eliminating Baseline Ghost Peaks
    Struggling with background noise in MS? Our high-purity silicone septa are platinum-cured to eliminate volatile siloxanes. This ensures that your vial septum won't interfere with sensitive analytical peaks, providing a clean baseline for every run.
    Protecting High-Cost Auto-Injectors
    Protecting High-Cost Auto-Injectors
    Frequent needle bending? For labs using fragile 32G needles, our customizable lab seals offer pre-slit options that reduce penetration force by 40%. This protects your robotic arm and prevents expensive instrument downtime.
    Maintaining Volatile Sample Integrity
    Maintaining Volatile Sample Integrity
    Sample concentration shifting overnight? The 8-425 small opening thread provides a tighter seal than 9mm alternatives. Our vial septum fits with zero clearance, stopping evaporation of volatile organic solvents during long sequences.
    Harsh Organic Solvent Resistance
    Harsh Organic Solvent Resistance
    Dealing with DCM or Hexane? Standard seals can swell or leach. Our customizable lab seals can be built with dual PTFE layers, providing a 100% inert barrier that maintains seal integrity even with the most aggressive lab chemicals.
    Batch Consistency for Audit Safety
    Batch Consistency for Audit Safety
    Worried about lab audit documentation? We provide full traceability for every batch of silicone septa. From raw material COA to final QC, we make procurement effortless for lab managers and QA auditors.

    24-Hour Confirmed Response & Dispatch Guarantee

    We guarantee a confirmed response within 24 hours for all inquiries. For in-stock vial septum, silicone septa, and accessories, orders dispatch within 24 working hours of confirmation. We support customer-specified logistics to ensure your customizable lab seals reach you via preferred carriers.

    Can I order customizable lab seals for specific instruments?

    Yes. We offer OEM services for cap colors, septa materials, and slit types. We guarantee a confirmed response within 24 hours for all custom feasibility requests.

    Is your silicone septa suitable for GC/MS?

    Absolutely. Our silicone septa are conditioned to remove impurities, ensuring ultra-low bleed and high sensitivity, which is critical for GC/MS and LC/MS trace analysis.

    How soon will my vial septum order ship?

    Standard in-stock items dispatch within 24 working hours. We maintain a large inventory of 8-425 closures to ensure your chromatography workflow never stops.

    Do you support specified forwarders?

    Yes, we support customer-specified logistics. Simply provide your account details (FedEx/DHL/UPS) or nominate your forwarder, and we will handle the rest.

    Are these closures compatible with Agilent vials?

    Our 8-425 closures follow the international GPI standard, ensuring 100% compatibility with all 8mm small opening vials from Agilent, Waters, and Shimadzu.

    Related articles

    Packing and Delivery

    Packing
    Packing
    Each vial is individually protected in shrink-wrapped trays, 100–200 pcs per inner box, then packed into corrugated export cartons.
    Labeling
    Labeling
    Each carton includes lot number and product information for traceability.
    Delivery Time
    Delivery Time
    Normally 7–15 working days after order confirmation.
    Shipping Options
    Shipping Options
    Air freight, sea freight, or express (DHL/UPS/FedEx) available upon request.
    Storage Condition
    Storage Condition
    Store in a clean, dry environment at room temperature.

    Company Profile

    Zhejiang Aijiren Technology Co., Ltd.
    A dedicated original manufacturer of chromatography and laboratory consumables.
    • 10,000+ m² modern facility with Class 100,000 cleanrooms

    • Automated production lines and rigorous in-house quality control

    • High-volume capacity, fast lead times, and reliable global supply

    • OEM/ODM customization with full batch traceability

    • Trusted by laboratories and analytical instrument brands worldwide

    VR Showroom

    OEM/ODM Custom Laboratory Consumables

    Aijiren turns your customized requirements—size, material, color, logo, or packaging—into reliable, ready-to-use products.
    OEM/ODM
    Precise manufacturing based on your drawings and specifications, with one-stop development support
    Confidentiality
    Full protection of all commercial information, molds, and designs
    Stable Supply
    Automated production ensures consistent quality and fast lead time
    Technical Support
    Dedicated team ensures smooth communication and hassle-free delivery

    FAQ From Customers (VR Display)

    What certificates do you have?

    Aijiren is certified to ISO 9001:2015 by SGS, ensuring controlled manufacturing processes and stable, fully traceable product quality.

    With continuous investment in R&D and multiple independent patents, we deliver high-performance and reliable consumables to laboratories worldwide.

     Some of the certificates of Aijiren are displayed

    What’s the MOQ? Do you accept small orders?

    Aijiren supports both standard and small batch orders. While MOQ varies by product type, we are happy to accommodate smaller quantities for trial, testing, or special projects. Please contact us for specific requirements.aijiren Quality control

    Is the quality guaranteed?

    All Aijiren products undergo random sampling and multiple in-house quality tests. Each batch is fully traceable, ensuring stable and reliable performance for your laboratory work.

     

    What kind of after-sales support does Aijiren provide?

    Aijiren provides practical after-sales support:

    ● Returns & replacements: Any product affecting use or sales can be returned or replaced.

    ● Technical support: Assistance with product use and troubleshooting.

    ● Order tracking & follow-up: We monitor shipments and follow up to ensure timely delivery.

    ● Dedicated contact: Aijiren provides a direct contact for after-sales inquiries.

    This ensures your laboratory work runs smoothly with minimal disruption.

     

    How long will it take for orders?

    The delivery time depends on the order quantity and whether customization is required:

    • In-stock products: shipped within 3–7 days after payment

    • Standard bulk orders: shipped within 2–4 weeks

    • OEM/ODM customized products: shipped within 3–5 weeks (depending on mold, logo, color, packaging, etc.)

    • Aijiren has automated production lines and a 100,000-class cleanroom, ensuring stable lead times and reliable supply.

    Are you a factory?(VR Display)

    Factory Exterior 360° VR
    Factory Exterior
    Die-Cutting Workshop 360° VR
    Die-Cutting Workshop
    Assembly Workshop 360° VR
    Assembly Workshop
    Printing Workshop 360° VR
    Printing Workshop
    Packaging Workshop 360° VR
    Packaging Workshop
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    Welcome To Contact Us

    Share your lab consumables customization needs—reach out for personalized support and detailed inquiry responses today!
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