Polytetrafluoroethylene (PTFE) provides a nearly universal chemical barrier, resisting aggressive acids, bases, alcohols, and organic solvents . Its stable carbon-fluorine molecular structure prevents solvent-induced degradation of the silicone matrix, ensuring no plasticizers or monomers leach into the sample.
The internal high-purity silicone layer offers exceptional resealing capabilities. Upon needle withdrawal, the silicone’s molecular memory quickly closes the puncture site, preventing air ingress or sample evaporation—vital for sequence analysis involving multiple injections .
For ultra-trace analysis (LC-MS/MS), our S113 Red PTFE/White Silicone/Red PTFE (TST) septa provide a dual-barrier system. The back-side PTFE layer locks in potential siloxane bleed, making it the cleanest sealing option for sensitive mass spectrometry workflows.
The S1111 and S1122 pre-slit septa are engineered for delicate, thin-gauge needles. By utilizing a "Y" or cross-slit design, the required penetration force is reduced by over 60%. This extends needle life and prevents the formation of a vacuum inside the vial during large-volume sample withdrawal .
These septa maintain physical integrity across a wide temperature spectrum from -60℃ to 210℃. They are equally stable in liquid nitrogen storage and high-temperature headspace heating environments .
| Part No. | Septa Configuration | Best Use Case | Chemical Resistance |
| S111 | White PTFE/Red Silicone | Routine HPLC/GC Analysis | High (Standard) |
| S112 | Red PTFE/White Silicone | High-sensitivity GC-FID | Ultra-High |
| S113 | Red PTFE/Silicone/Red PTFE | Ultratrace Analysis (LC-MS/MS) | Maximum (TST) |
| S115 | Nature PTFE/Red Rubber | Economical Routine QC | Moderate |
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Part No. |
Cap Color | Purpose in GLP | Material Type |
| C111 | Silver (Standard) | General Inventory & Large Batches | Anodized Aluminum |
| SC112112 | Red | Urgent Samples / Hazard Identification | Anodized Aluminum |
| SC112113 | Blue | Calibrators / Blanks Identification | Anodized Aluminum |
| SC112114 | Gold | Specified Control Samples | Anodized Aluminum |
| Part No. | Configuration | Efficiency Benefit | Target System |
| S1111 | Pre-slit Septa Only | Prevents Vacuum, Protects Needles | High-Throughput |
| SC111111 | Pre-assembled (Cap+Septa) | Eliminates Lab Handling Contamination | Certified Robotics |
| SC1111111 | Pre-assembled + Pre-slit | Maximum Convenience & Safety | MS/MS Systems |
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