8-425 Screw Neck Vials ND8

Description

Feature

Specification

Application

Product

FAQ

Packing and Delivery

Overview

The ND8 8-425 series is the gold standard for laboratories requiring high-precision sealing in narrow-neck configurations.

Engineered with a 7.0 or 5.0 expansion coefficient, these vials minimize sample-to-glass interaction, ensuring peak integrity during sensitive chemical analysis.

Nd8 Application

Versatile sample storage and analysis for demanding environments.

Chemical Inertness: USP Type I glass prevents pH shifts.

Thermal Stability: High resistance to temperature fluctuations.

Precision Threading: 8-425 finish eliminates cap tilting.

Uniform Bottom: Flat base ensures optimal vial movement in autosamplers.

UV Protection: Amber glass options for light-sensitive compounds.

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Ordering Specification Table

Strategic Sourcing & Technical Selection Guide

Glass Grade & Chemical Resistance Comparison

Caps & Septa Pairing Guide

Ensuring that 8-425 vials fit your specific robotic arm and needle depth is critical to preventing laboratory downtime. While ND9 vials are "Short Thread," the 8-425 ND8 series is a standard thread designed for precision narrow-neck instruments. Use the table below to verify compatibility with your existing hardware.

Instrument Brand	Compatibility	Recommended Series
Shimadzu	Full Compatibility	SIL-20/30/40 Nexera/Prominence
Hitachi	Full Compatibility	L-2000 / LaChrom Elite
Varian	Full Compatibility	8100/8200/8400 Series
Jasco	Full Compatibility	AS-2050 / AS-2055 / AS-4050
Agilent	Use with Adapter	For 11mm Tray (Not Recommended for ND8)

Not all borosilicate glass is equal. The expansion coefficient directly impacts the pH stability of your sample and the vial's resistance to thermal shock. For high-sensitivity chromatography, selecting the correct glass type prevents unwanted ion leaching and peak interference.

Feature	5.0 Type Borosilicate (USP I)	7.0 Type Borosilicate (USP I)
Hydrolytic Resistance	Superior (Grade 1)	High (Grade 1)
Expansion Coefficient	50 x 10-7/K	70 x 10-7/K
pH Drift Risk	Minimal (Ideal for trace analysis)	Low (Suitable for routine tests)
Best For	Sensitive pharmaceutical analytes	Standard environmental/food testing
Cost Performance	Premium Grade	Cost-Effective

A vial is only as good as its seal. Choosing the wrong septa can lead to sample contamination or needle damage. This guide helps procurement managers match the correct 8-425 closure system to the specific solvents and injection frequencies used in your laboratory.

Solvent Type	Recommended Septa	Property
Acids, Bases, Alcohols	PTFE / Silicone (White/Red)	Excellent resealability for multiple injections
Aggressive Organics	PTFE / Silicone / PTFE	Double-sided protection against corrosion
High Volatility	Integral Bonded Septa	Prevents septa displacement during puncture
Single Injection	PTFE only (Thin)	Economical but offers no resealing capability
Easy Puncture	Pre-slit Septa (Pre-cut)	Protects fragile/thin needles from bending

Professional Solutions

Precision-Engineered Solutions for Complex Chromatographic Workflows.

Seamless Integration with Robotic Arms

The 8-425 thread is specifically calibrated for narrow-neck systems like Shimadzu and Hitachi. Our vials undergo rigorous dimensional testing to ensure that robotic grippers can position them without jams or mechanical errors during high-throughput sequences.

Advanced Silanization for Reactive Analytes

For labs dealing with proteins, phenols, or other polar compounds, our silanized 8-425 vials provide a deactivated surface. This prevents sample adsorption on the glass wall, ensuring maximum recovery and peak reproducibility in trace analysis.

Exceptional Sealing Against Evaporation

Standard 8-425 openings minimize the headspace and surface area exposed during puncture. When paired with our high-resiliency PTFE/Silicone septa, it maintains vacuum integrity even during prolonged 24-hour sequence runs with highly volatile solvents.

Uniform Amber Glass for UV Shielding

Our amber vials are manufactured using high-quality USP Type I glass with consistent wall thickness. This provides reliable UV protection for vitamins, catecholamines, and other light-sensitive analytes, preventing sample degradation during storage.

Certified Cleanliness for Trace Analysis

Produced in ISO-certified cleanroom environments, every batch of ND8 vials is free from organic contaminants. The clear write-on spot allows for precise manual labeling, essential for maintaining strict GLP/GMP traceability in pharmaceutical labs.

Expert Troubleshooting & FAQ

To assist our procurement partners and laboratory technicians in making informed decisions, we have compiled the most critical technical questions regarding the 8-425 (ND8) screw neck vial system.